TNFSF18 anticorps
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- Antigène Voir toutes TNFSF18 Anticorps
- TNFSF18 (Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TNFSF18 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Specificité
- TNF18 antibody detects endogenous levels of total TNF18
- Réactivité croisée
- Humain
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide
- Isotype
- IgG
- Top Product
- Discover our top product TNFSF18 Anticorps primaire
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- Indications d'application
- WB 1:500-1:2000 IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Antigène
- TNFSF18 (Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18))
- Autre désignation
- TNF18 (TNFSF18 Produits)
- Synonymes
- anticorps Gitrl, anticorps AITRL, anticorps GITRL, anticorps TL6, anticorps hGITRL, anticorps TNLG2A, anticorps tumor necrosis factor (ligand) superfamily, member 18, anticorps TNF superfamily member 18, anticorps Tnfsf18, anticorps TNFSF18
- Sujet
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Description: Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B. Triggers increased phosphorylation of STAT1 and up-regulates expression of VCAM1 and ICAM1 (PubMed:23892569). Promotes leukocyte adhesion to endothelial cells (PubMed:23892569). Regulates migration of monocytes from the splenic reservoir to sites of inflammation (By similarity).
Gene: TNFSF18
- Poids moléculaire
- 72 kDa
- ID gène
- 8995
- UniProt
- Q9UNG2
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