SH2B2 anticorps (N-Term)
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- Antigène Voir toutes SH2B2 Anticorps
- SH2B2 (SH2B Adaptor Protein 2 (SH2B2))
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Épitope
- N-Term
- Reactivité
- Humain, Rat, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SH2B2 est non-conjugé
- Application
- ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificité
- SH2B2 Antibody detects endogenous levels of total SH2B2.
- Homologie
- Pig,Zebrafish,Bovine,Horse,Rabbit,Dog,Chicken,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human SH2B2, corresponding to a region within N-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product SH2B2 Anticorps primaire
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- Indications d'application
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- SH2B2 (SH2B Adaptor Protein 2 (SH2B2))
- Autre désignation
- SH2B2 (SH2B2 Produits)
- Synonymes
- anticorps APS, anticorps Aps, anticorps SH2B adaptor protein 2, anticorps SH2B2, anticorps Sh2b2
- Sujet
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Description: Adapter protein for several members of the tyrosine kinase receptor family. Involved in multiple signaling pathways. May be involved in coupling from immunoreceptor to Ras signaling. Acts as a negative regulator of cytokine signaling in collaboration with CBL. Binds to EPOR and suppresses EPO-induced STAT5 activation, possibly through a masking effect on STAT5 docking sites in EPOR. Suppresses PDGF-induced mitogenesis. May induce cytoskeletal reorganization via interaction with VAV3.
Gene: SH2B2
- Poids moléculaire
- 67 kDa
- ID gène
- 10603
- UniProt
- O14492
- Pathways
- Carbohydrate Homeostasis, Brown Fat Cell Differentiation
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