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SH2B2 anticorps (N-Term)

SH2B2 Reactivité: Humain, Rat, Souris ELISA, WB, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6256908
  • Antigène Voir toutes SH2B2 Anticorps
    SH2B2 (SH2B Adaptor Protein 2 (SH2B2))
    Épitope
    • 2
    • 1
    N-Term
    Reactivité
    Humain, Rat, Souris
    Hôte
    • 11
    • 1
    Lapin
    Clonalité
    • 11
    • 1
    Polyclonal
    Conjugué
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SH2B2 est non-conjugé
    Application
    ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    SH2B2 Antibody detects endogenous levels of total SH2B2.
    Homologie
    Pig,Zebrafish,Bovine,Horse,Rabbit,Dog,Chicken,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human SH2B2, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product SH2B2 Anticorps primaire
  • Indications d'application
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    SH2B2 (SH2B Adaptor Protein 2 (SH2B2))
    Autre désignation
    SH2B2 (SH2B2 Produits)
    Synonymes
    anticorps APS, anticorps Aps, anticorps SH2B adaptor protein 2, anticorps SH2B2, anticorps Sh2b2
    Sujet

    Description: Adapter protein for several members of the tyrosine kinase receptor family. Involved in multiple signaling pathways. May be involved in coupling from immunoreceptor to Ras signaling. Acts as a negative regulator of cytokine signaling in collaboration with CBL. Binds to EPOR and suppresses EPO-induced STAT5 activation, possibly through a masking effect on STAT5 docking sites in EPOR. Suppresses PDGF-induced mitogenesis. May induce cytoskeletal reorganization via interaction with VAV3.

    Gene: SH2B2

    Poids moléculaire
    67 kDa
    ID gène
    10603
    UniProt
    O14492
    Pathways
    Carbohydrate Homeostasis, Brown Fat Cell Differentiation
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