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BMP10 anticorps (Internal Region)

BMP10 Reactivité: Humain WB, ELISA, ICC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6256960
  • Antigène Voir toutes BMP10 Anticorps
    BMP10 (Bone Morphogenetic Protein 10 (BMP10))
    Épitope
    • 15
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivité
    • 60
    • 24
    • 24
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 52
    • 7
    • 1
    • 1
    Lapin
    Clonalité
    • 55
    • 6
    Polyclonal
    Conjugué
    • 33
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp BMP10 est non-conjugé
    Application
    • 47
    • 16
    • 14
    • 13
    • 8
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificité
    BMP10 Antibody detects endogenous levels of total BMP10.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human BMP10, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product BMP10 Anticorps primaire
  • Indications d'application
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    BMP10 (Bone Morphogenetic Protein 10 (BMP10))
    Autre désignation
    BMP10 (BMP10 Produits)
    Synonymes
    anticorps BMP10, anticorps si:dkey-13n15.5, anticorps Bmp10, anticorps BMP9, anticorps BMP-10, anticorps bone morphogenetic protein 10, anticorps BMP10, anticorps bmp10, anticorps LOC662386, anticorps Bmp10
    Sujet

    Description: Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.

    Gene: BMP10

    Poids moléculaire
    48 kDa
    ID gène
    27302
    UniProt
    O95393
    Pathways
    Hormone Activity, Regulation of Muscle Cell Differentiation
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