BMP10 anticorps (Internal Region)
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- Antigène Voir toutes BMP10 Anticorps
- BMP10 (Bone Morphogenetic Protein 10 (BMP10))
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Épitope
- Internal Region
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp BMP10 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
- Specificité
- BMP10 Antibody detects endogenous levels of total BMP10.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human BMP10, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product BMP10 Anticorps primaire
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- Indications d'application
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- BMP10 (Bone Morphogenetic Protein 10 (BMP10))
- Autre désignation
- BMP10 (BMP10 Produits)
- Synonymes
- anticorps BMP10, anticorps si:dkey-13n15.5, anticorps Bmp10, anticorps BMP9, anticorps BMP-10, anticorps bone morphogenetic protein 10, anticorps BMP10, anticorps bmp10, anticorps LOC662386, anticorps Bmp10
- Sujet
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Description: Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.
Gene: BMP10
- Poids moléculaire
- 48 kDa
- ID gène
- 27302
- UniProt
- O95393
- Pathways
- Hormone Activity, Regulation of Muscle Cell Differentiation
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