CBR1 anticorps (C-Term)

N° du produit ABIN6257012

Détail du produit anti-CBR1 anticorps

Antigène: CBR1 (Carbonyl Reductase 1 (CBR1))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CBR1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: CBR1 Antibody detects endogenous levels of total CBR1.

Homologie: Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human CBR1, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur CBR1

Antigène: CBR1 (Carbonyl Reductase 1 (CBR1))

Autre désignation: CBR1 (CBR1 Produits)

Synonymes: anticorps LOC100222525, anticorps MGC131152, anticorps CBR, anticorps SDR21C1, anticorps hCBR1, anticorps 9-KPR, anticorps AW261796, anticorps CR, anticorps Cbr, anticorps carbonyl reductase 1, anticorps carbonyl reductase [NADPH] 1, anticorps carbonyl reductase 1 S homeolog, anticorps carbonyl reductase, anticorps cbr1, anticorps CBR1, anticorps LOC100222525, anticorps cbr1.S, anticorps Smp_033530.3, anticorps LOC610164, anticorps Cbr1

Sujet:

Description: NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione.

Gene: CBR1

Poids moléculaire: 32 kDa

ID gène: 873

UniProt: P16152