ADCY6 anticorps (Internal Region)

N° du produit ABIN6257031

Détail du produit anti-ADCY6 anticorps

Antigène: ADCY6 (Adenylate Cyclase 6 (ADCY6))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADCY6 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificité: ADCY5/6 Antibody detects endogenous levels of total ADCY5/6.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human ADCY5/6, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur ADCY6

Antigène: ADCY6 (Adenylate Cyclase 6 (ADCY6))

Autre désignation: ADCY5,ADCY6 (ADCY6 Produits)

Synonymes: anticorps ADCY6, anticorps adcy6, anticorps AC6, anticorps mKIAA0422, anticorps ACVI, anticorps ADCYB, anticorps adenylate cyclase 6 L homeolog, anticorps adenylate cyclase 6, anticorps adenylate cyclase 6a, anticorps adcy6.L, anticorps ADCY6, anticorps adcy6a, anticorps adcy6, anticorps Adcy6

Sujet:

Description: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling (PubMed:15385642, PubMed:26206488, PubMed:24700542). Mediates signaling downstream of ADRB1 (PubMed:24700542). Regulates the increase of free cytosolic Ca2+ in response to increased blood glucose levels and contributes to the regulation of Ca2+-dependent insulin secretion (PubMed:24740569).

Gene: ADCY5

Poids moléculaire: 138 kDa

ID gène: 111, 112

UniProt: O95622, O43306

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma