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DRD4 anticorps (C-Term)

DRD4 Reactivité: Humain, Souris, Rat WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6257148
  • Antigène Voir toutes DRD4 Anticorps
    DRD4 (Dopamine Receptor D4 (DRD4))
    Épitope
    • 15
    • 8
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 60
    • 42
    • 10
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 53
    • 10
    • 1
    Lapin
    Clonalité
    • 53
    • 10
    Polyclonal
    Conjugué
    • 26
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DRD4 est non-conjugé
    Application
    • 48
    • 26
    • 13
    • 13
    • 7
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    DRD4 Antibody detects endogenous levels of total DRD4.
    Homologie
    Pig,Bovine,Horse,Chicken,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human DRD4, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product DRD4 Anticorps primaire
  • Indications d'application
    WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    DRD4 (Dopamine Receptor D4 (DRD4))
    Autre désignation
    DRD4 (DRD4 Produits)
    Synonymes
    anticorps Drd4b, anticorps si:ch211-69h5.1, anticorps zgc:123021, anticorps D4DR, anticorps AW125663, anticorps D4R, anticorps Drd-4, anticorps D4RA, anticorps DRD4, anticorps Drd4c, anticorps dopamine receptor D4 related sequence, anticorps dopamine receptor D4, anticorps dopamine receptor D4b, anticorps drd4-rs, anticorps DRD4, anticorps Drd4, anticorps SRU_2808, anticorps MSMEG_3522, anticorps drd4b
    Sujet

    Description: Dopamine receptor responsible for neuronal signaling in the mesolimbic system of the brain, an area of the brain that regulates emotion and complex behavior. Activated by dopamine, but also by epinephrine and norepinephrine, and by numerous synthetic agonists and drugs (PubMed:9003072, PubMed:16423344, PubMed:27659709, PubMed:29051383). Agonist binding triggers signaling via G proteins that inhibit adenylyl cyclase (PubMed:7512953, PubMed:7643093, PubMed:16423344, PubMed:27659709, PubMed:29051383). Modulates the circadian rhythm of contrast sensitivity by regulating the rhythmic expression of NPAS2 in the retinal ganglion cells (By similarity).

    Gene: DRD4

    Poids moléculaire
    48 kDa
    ID gène
    1815
    UniProt
    P21917
    Pathways
    cAMP Metabolic Process, Synaptic Membrane, Proton Transport, Photoperiodism, Negative Regulation of Transporter Activity
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