EIF3F anticorps (Internal Region)

N° du produit ABIN6257159

Détail du produit anti-EIF3F anticorps

Antigène: EIF3F (Eukaryotic Translation Initiation Factor 3 Subunit F (EIF3F))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EIF3F est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: EIF3F Antibody detects endogenous levels of total EIF3F.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human EIF3F, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur EIF3F

Antigène: EIF3F (Eukaryotic Translation Initiation Factor 3 Subunit F (EIF3F))

Autre désignation: EIF3F (EIF3F Produits)

Synonymes: anticorps AO090005001590, anticorps Dmel\CG9769, anticorps eIF3-S5, anticorps eif3f, anticorps LOC733116, anticorps eIF3f, anticorps EIF3S5, anticorps eIF3-p47, anticorps 0610037M02Rik, anticorps AA409853, anticorps Eif3s5, anticorps eukaryotic translation initiation factor 3 subunit F, anticorps hypothetical protein, anticorps CG9769 gene product from transcript CG9769-RA, anticorps eukaryotic translation initiation factor 3 subunit 5, anticorps eukaryotic translation initiation factor 3, subunit F, anticorps Eukaryotic translation initiation factor 3 subunit F, anticorps eif3f, anticorps ANI_1_120074, anticorps AOR_1_2780174, anticorps PTRG_03897, anticorps PAAG_00376, anticorps MCYG_08502, anticorps MGYG_08653, anticorps PGTG_04587, anticorps CG9769, anticorps LOC733116, anticorps EIF3F, anticorps Eif3f, anticorps eif-3.F

Sujet:

Description: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:17581632, PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773).

Gene: EIF3F

Poids moléculaire: 38 kDa

ID gène: 8665

UniProt: O00303

Pathways: Ribonucleoprotein Complex Subunit Organization