ELL anticorps (Internal Region)

N° du produit ABIN6257163

Détail du produit anti-ELL anticorps

Antigène: ELL (Elongation Factor RNA Polymerase II (ELL))

Épitope: Internal Region

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ELL est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: ELL Antibody detects endogenous levels of total ELL.

Homologie: Pig,Zebrafish,Bovine,Horse,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human ELL, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur ELL

Antigène: ELL (Elongation Factor RNA Polymerase II (ELL))

Autre désignation: ELL (ELL Produits)

Synonymes: anticorps wu:fc60b11, anticorps zgc:63836, anticorps C19orf17, anticorps ELL1, anticorps MEN, anticorps PPP1R68, anticorps Ell1, anticorps Men, anticorps elongation factor for RNA polymerase II, anticorps elongation factor RNA polymerase II, anticorps ELL, anticorps ell, anticorps Ell

Sujet:

Description: Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Elongation factor component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:22195968, PubMed:23932780). Specifically required for stimulating the elongation step of RNA polymerase II- and III-dependent snRNA gene transcription (PubMed:23932780). ELL also plays an early role before its assembly into in the SEC complex by stabilizing RNA polymerase II recruitment/initiation and entry into the pause site. Required to stabilize the pre-initiation complex and early elongation.

Gene: ELL

Poids moléculaire: 65 kDa

ID gène: 8178

UniProt: P55199