FGF19 anticorps (C-Term)

N° du produit ABIN6257192

Détail du produit anti-FGF19 anticorps

Antigène: FGF19 (Fibroblast Growth Factor 19 (FGF19))

Épitope: C-Term

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FGF19 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: FGF19 Antibody detects endogenous levels of total FGF19.

Homologie: Pig,Zebrafish,Bovine,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human FGF19, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Date de péremption: 12 months

Détails sur FGF19

Antigène: FGF19 (Fibroblast Growth Factor 19 (FGF19))

Autre désignation: FGF19 (FGF19 Produits)

Synonymes: anticorps FGF-19, anticorps Fgf15, anticorps fibroblast growth factor 19, anticorps FGF19, anticorps Fgf19, anticorps fgf19

Sujet:

Description: Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4.

Gene: FGF19

Poids moléculaire: 24 kDa,

ID gène: 9965

UniProt: O95750

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway