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FOXN4 anticorps (C-Term)

FOXN4 Reactivité: Humain WB, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6257195
  • Antigène Voir toutes FOXN4 Anticorps
    FOXN4 (Forkhead Box N4 (FOXN4))
    Épitope
    • 13
    • 7
    • 7
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 43
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 43
    Lapin
    Clonalité
    • 43
    Polyclonal
    Conjugué
    • 19
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp FOXN4 est non-conjugé
    Application
    • 33
    • 26
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    FOXN4 Antibody detects endogenous levels of total FOXN4.
    Homologie
    Pig,Bovine,Sheep,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human FOXN4, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
  • Indications d'application
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    FOXN4 (Forkhead Box N4 (FOXN4))
    Autre désignation
    FOXN4 (FOXN4 Produits)
    Synonymes
    anticorps whn, anticorps whna, anticorps forkhead box N4, anticorps forkhead box N4 S homeolog, anticorps FOXN4, anticorps foxn4, anticorps Foxn4, anticorps foxn4.S
    Sujet

    Description: Transcription factor essential for neural and some non-neural tissues development, such as retina and lung respectively. Binds to an 11-bp consensus sequence containing the invariant tetranucleotide 5'-ACGC-3'. During development of the central nervous system, is required to specify the amacrine and horizontal cell fates from multipotent retinal progenitors while suppressing the alternative photoreceptor cell fates through activating DLL4-NOTCH signaling. Also acts synergistically with ASCL1/MASH1 to activate DLL4-NOTCH signaling and drive commitment of p2 progenitors to the V2b interneuron fates during spinal cord neurogenesis. In development of non-neural tissues, plays an essential role in the specification of the atrioventricular canal and is indirectly required for patterning the distal airway during lung development (By similarity).

    Gene: FOXN4

    Poids moléculaire
    50 kDa
    ID gène
    121643
    UniProt
    Q96NZ1
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