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GDF15 anticorps (N-Term)

GDF15 Reactivité: Humain WB, ELISA, IHC, ICC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6257251
  • Antigène Voir toutes GDF15 Anticorps
    GDF15 (Growth Differentiation Factor 15 (GDF15))
    Épitope
    • 16
    • 15
    • 11
    • 8
    • 7
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 94
    • 28
    • 21
    • 1
    • 1
    Humain
    Hôte
    • 88
    • 13
    • 3
    • 1
    Lapin
    Clonalité
    • 89
    • 15
    • 1
    Polyclonal
    Conjugué
    • 50
    • 14
    • 10
    • 8
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GDF15 est non-conjugé
    Application
    • 84
    • 52
    • 36
    • 18
    • 13
    • 13
    • 8
    • 7
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificité
    GDF15 Antibody detects endogenous levels of total GDF15.
    Homologie
    Pig,Bovine,Sheep,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human GDF15, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product GDF15 Anticorps primaire
  • Indications d'application
    WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    GDF15 (Growth Differentiation Factor 15 (GDF15))
    Autre désignation
    GDF15 (GDF15 Produits)
    Synonymes
    anticorps GDF15, anticorps GDF-15, anticorps MIC-1, anticorps MIC1, anticorps NAG-1, anticorps PDF, anticorps PLAB, anticorps PTGFB, anticorps SBF, anticorps growth differentiation factor 15, anticorps GDF15, anticorps Gdf15
    Sujet

    Description: Regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099, PubMed:23468844, PubMed:29046435). Binds to its receptor, GFRAL, and activates GFRAL-expressing neurons localized in the area postrema and nucleus tractus solitarius of the brainstem (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099). It then triggers the activation of neurons localized within the parabrachial nucleus and central amygdala, which contitutes part of the 'emergency circuit' that shapes feeding responses to stressful conditions (PubMed:28953886). On hepatocytes, inhibits growth hormone signaling (By similarity).

    Gene: GDF15

    Poids moléculaire
    37 kDa
    ID gène
    9518
    UniProt
    Q99988
    Pathways
    SARS-CoV-2 Protein Interactome
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