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IL-11 anticorps (N-Term)

IL11 Reactivité: Humain, Souris, Rat WB, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6257286
  • Antigène Voir toutes IL-11 (IL11) Anticorps
    IL-11 (IL11) (Interleukin 11 (IL11))
    Épitope
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    Humain, Souris, Rat
    Hôte
    • 47
    • 18
    • 1
    • 1
    Lapin
    Clonalité
    • 48
    • 19
    Polyclonal
    Conjugué
    • 32
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp IL-11 est non-conjugé
    Application
    • 47
    • 33
    • 17
    • 13
    • 13
    • 10
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA
    Specificité
    IL11 Antibody detects endogenous levels of total IL11.
    Homologie
    Pig,Bovine,Horse,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human IL11, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product IL11 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Date de péremption
    12 months
  • Antigène
    IL-11 (IL11) (Interleukin 11 (IL11))
    Autre désignation
    IL11 (IL11 Produits)
    Synonymes
    anticorps IL11, anticorps AGIF, anticorps IL-11, anticorps Il-11, anticorps interleukin 11, anticorps IL11, anticorps Il11
    Sujet

    Description: Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed:2145578). Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation (PubMed:12919066). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3.

    Gene: IL11

    Poids moléculaire
    27 kDa
    ID gène
    3589
    UniProt
    P20809
    Pathways
    Signalistation JAK/STAT, Negative Regulation of Hormone Secretion
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