Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

MYO9B anticorps (N-Term)

MYO9B Reactivité: Humain, Souris, Rat WB, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6257337
  • Antigène Voir toutes MYO9B Anticorps
    MYO9B (Myosin IXB (MYO9B))
    Épitope
    • 2
    • 1
    • 1
    N-Term
    Reactivité
    Humain, Souris, Rat
    Hôte
    • 11
    • 1
    Lapin
    Clonalité
    • 12
    Polyclonal
    Conjugué
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MYO9B est non-conjugé
    Application
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    MYO9B Antibody detects endogenous levels of total MYO9B.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human MYO9B, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
  • Indications d'application
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    MYO9B (Myosin IXB (MYO9B))
    Autre désignation
    MYO9B (MYO9B Produits)
    Synonymes
    anticorps CELIAC4, anticorps MYR5, anticorps MYO9B, anticorps fb53f01, anticorps wu:fb53f01, anticorps wu:fc47c07, anticorps si:dkeyp-66d1.8, anticorps myosin IXB, anticorps myosin IXb, anticorps unconventional myosin-IXb, anticorps MYO9B, anticorps Myo9b, anticorps myo9b, anticorps LOC100450445
    Sujet

    Description: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Binds actin with high affinity both in the absence and presence of ATP and its mechanochemical activity is inhibited by calcium ions (PubMed:9490638). Also acts as a GTPase activator for RHOA (PubMed:9490638, PubMed:26529257). Plays a role in the regulation of cell migration via its role as RHOA GTPase activator. This is regulated by its interaction with the SLIT2 receptor ROBO1, interaction with ROBO1 impairs interaction with RHOA and subsequent activation of RHOA GTPase activity, and thereby leads to increased levels of active, GTP-bound RHOA (PubMed:26529257).

    Gene: MYO9B

    Poids moléculaire
    250 kDa
    ID gène
    4650
    UniProt
    Q13459
Vous êtes ici:
Support technique