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MAPKSP1 anticorps (Internal Region)

MAPKSP1 Reactivité: Humain, Souris, Rat WB, ELISA, ICC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6257364
  • Antigène Voir toutes MAPKSP1 Anticorps
    MAPKSP1 (Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1))
    Épitope
    • 15
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivité
    • 26
    • 18
    • 11
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 30
    • 3
    Lapin
    Clonalité
    • 30
    • 3
    Polyclonal
    Conjugué
    • 12
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MAPKSP1 est non-conjugé
    Application
    • 13
    • 13
    • 11
    • 10
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificité
    LAMTOR3 Antibody detects endogenous levels of total LAMTOR3.
    Homologie
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human LAMTOR3, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product MAPKSP1 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000, IF/ICC 1:100-1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Date de péremption
    12 months
  • Antigène
    MAPKSP1 (Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1))
    Autre désignation
    LAMTOR3 (MAPKSP1 Produits)
    Synonymes
    anticorps MAPKSP1, anticorps MAP2K1IP1, anticorps MAPBP, anticorps MP1, anticorps PRO0633, anticorps Ragulator3, anticorps AW556229, anticorps Map2k1ip1, anticorps Mapbp, anticorps Mapksp1, anticorps Mp1, anticorps mapksp1, anticorps zgc:110207, anticorps late endosomal/lysosomal adaptor, MAPK and MTOR activator 3, anticorps LAMTOR3, anticorps Lamtor3, anticorps lamtor3
    Sujet

    Description: As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Adapter protein that enhances the efficiency of the MAP kinase cascade facilitating the activation of MAPK2.

    Gene: LAMTOR3

    ID gène
    8649
    UniProt
    Q9UHA4
    Pathways
    Signalisation PI3K-Akt
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