KCNK4 anticorps (C-Term)

N° du produit ABIN6257437

Détail du produit anti-KCNK4 anticorps

Antigène: KCNK4 (Potassium Channel, Subfamily K, Member 4 (KCNK4))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCNK4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: KCNK4 Antibody detects endogenous levels of total KCNK4.

Homologie: Pig,Bovine,Horse,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human KCNK4, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur KCNK4

Antigène: KCNK4 (Potassium Channel, Subfamily K, Member 4 (KCNK4))

Autre désignation: KCNK4 (KCNK4 Produits)

Synonymes: anticorps K2p4.1, anticorps TRAAK, anticorps TRAAK1, anticorps MLZ-622, anticorps TRAAKt, anticorps Tex40, anticorps KT4.1, anticorps potassium two pore domain channel subfamily K member 4, anticorps potassium channel, subfamily K, member 4, anticorps KCNK4, anticorps Kcnk4

Sujet:

Description: Voltage-insensitive potassium channel (PubMed:22282805). Channel opening is triggered by mechanical forces that deform the membrane (PubMed:22282805, PubMed:25471887, PubMed:25500157). Channel opening is triggered by raising the intracellular  pH to basic levels (By similarity). The channel is inactive at 24 degrees Celsius (in vitro), raising the temperature to 37 degrees Celsius increases the frequency of channel opening, with a further increase in channel activity when the temperature is raised to 42 degrees Celsius (By similarity). Plays a role in the perception of pain caused by heat (By similarity). Plays a role in the sensory perception of pain caused by pressure (By similarity).

Gene: KCNK4

Poids moléculaire: 45 kDa

ID gène: 50801

UniProt: Q9NYG8