SHB anticorps (C-Term)

N° du produit ABIN6257494

Détail du produit anti-SHB anticorps

Antigène: SHB (Src Homology 2 Domain Containing Adaptor Protein B (SHB))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SHB est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificité: SHB Antibody detects endogenous levels of total SHB.

Homologie: Pig,Bovine,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human SHB, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur SHB

Antigène: SHB (Src Homology 2 Domain Containing Adaptor Protein B (SHB))

Autre désignation: SHB (SHB Produits)

Synonymes: anticorps SHB, anticorps RP11-3J10.8, anticorps bA3J10.2, anticorps RGD1565350, anticorps BC028832, anticorps SH2 domain containing adaptor protein B, anticorps src homology 2 domain-containing transforming protein B, anticorps SHB, anticorps Shb

Sujet:

Description: Adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. May play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. May also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. May also regulate IRS1 and IRS2 signaling in insulin-producing cells.

Gene: SHB

Poids moléculaire: 55 kDa

ID gène: 6461

UniProt: Q15464