TBP anticorps (N-Term)

N° du produit ABIN6257528

Détail du produit anti-TBP anticorps

Antigène: TBP (TATA Box Binding Protein (TBP))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TBP est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: TBP Antibody detects endogenous levels of total TBP.

Homologie: Pig,Zebrafish,Bovine,Horse,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human TBP, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur TBP

Antigène: TBP (TATA Box Binding Protein (TBP))

Autre désignation: TBP (TBP Produits)

Synonymes: anticorps GTF2D, anticorps GTF2D1, anticorps HDL4, anticorps SCA17, anticorps TFIID, anticorps Gtf2d, anticorps fd20h06, anticorps si:zc101n13.2, anticorps wu:fd20h06, anticorps zgc:66213, anticorps TBP1, anticorps TBP, anticorps tbp, anticorps CG9874, anticorps Dmel\\CG9874, anticorps RBP, anticorps TBP38, anticorps TFIIDtau, anticorps TfIID, anticorps dTBP, anticorps dTFIID, anticorps dTbp, anticorps dtbp, anticorps gtf2d, anticorps gtf2d1, anticorps sca17, anticorps tfiid, anticorps tfiidtau, anticorps xtbp, anticorps tbp-a, anticorps tbp-b, anticorps TATA-box binding protein, anticorps TATA box binding protein, anticorps TATA binding protein, anticorps TATA-box binding protein L homeolog, anticorps TATA-box-binding protein, anticorps TATA-box binding protein S homeolog, anticorps TBP, anticorps Tbp, anticorps tbp, anticorps tbp.L, anticorps tbp.S

Sujet:

Description: General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID (PubMed:2374612, PubMed:2363050, PubMed:2194289, PubMed:9836642, PubMed:27193682). Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II (PubMed:2374612, PubMed:2363050, PubMed:2194289, PubMed:9836642, PubMed:27193682). Component of a BRF2-containing transcription factor complex that regulates transcription mediated by RNA polymerase III (PubMed:26638071). Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (pre-initiation complex) during RNA polymerase I-dependent transcription (PubMed:15970593). The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA.

Gene: TBP

Poids moléculaire: 38 kDa

ID gène: 6908

UniProt: P20226

Pathways: Signalisation WNT