ZFYVE19 anticorps (Internal Region)

N° du produit ABIN6257582

Détail du produit anti-ZFYVE19 anticorps

Antigène: ZFYVE19 (Zinc Finger, FYVE Domain Containing 19 (ZFYVE19))

Épitope: Internal Region

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZFYVE19 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: ZFYVE19 Antibody detects endogenous levels of total ZFYVE19.

Homologie: Horse,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human ZFYVE19, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur ZFYVE19

Antigène: ZFYVE19 (Zinc Finger, FYVE Domain Containing 19 (ZFYVE19))

Autre désignation: ZFYVE19 (ZFYVE19 Produits)

Synonymes: anticorps ZFYVE19, anticorps mpfyve, anticorps DKFZp469E1112, anticorps MPFYVE, anticorps 1500041L05Rik, anticorps zinc finger FYVE-type containing 19, anticorps zinc finger FYVE domain containing 19, anticorps zinc finger, FYVE domain containing 19, anticorps ZFYVE19, anticorps Zfyve19, anticorps zfyve19

Sujet:

Description: Key regulator of abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Together with CHMP4C, required to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Deactivation of AURKB results in dephosphorylation of CHMP4C followed by its dissociation from ZFYVE19/ANCHR and VPS4 and subsequent abscission.

Gene: ZFYVE19

Poids moléculaire: 50 kDa

ID gène: 84936

UniProt: Q96K21