Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

KSR2 anticorps (Internal Region)

KSR2 Reactivité: Humain, Souris ELISA, WB, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6257612
  • Antigène Voir toutes KSR2 Anticorps
    KSR2 (Kinase Suppressor of Ras 2 (KSR2))
    Épitope
    • 8
    • 8
    • 7
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Internal Region
    Reactivité
    Humain, Souris
    Hôte
    • 40
    • 6
    Lapin
    Clonalité
    • 43
    • 3
    Polyclonal
    Conjugué
    • 20
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp KSR2 est non-conjugé
    Application
    • 34
    • 30
    • 16
    • 13
    • 8
    • 6
    • 2
    • 1
    ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    KSR2 Antibody detects endogenous levels of total KSR2.
    Homologie
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Chicken,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human KSR2, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product KSR2 Anticorps primaire
  • Indications d'application
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    KSR2 (Kinase Suppressor of Ras 2 (KSR2))
    Autre désignation
    KSR2 (KSR2 Produits)
    Synonymes
    anticorps kinase suppressor of ras 2, anticorps KSR2, anticorps Ksr2
    Sujet

    Description: Location-regulated scaffold connecting MEK to RAF. Has very low protein kinase activity and can phosphorylate MAP2K1 at several Ser and Thr residues with very low efficiency (in vitro). Interaction with BRAF enhances KSR2-mediated phosphorylation of MAP2K1 (in vitro). Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production.

    Gene: KSR2

    Poids moléculaire
    108 kDa
    ID gène
    283455
    UniProt
    Q6VAB6
Vous êtes ici:
Support technique