AKAP10 anticorps (N-Term)
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- Antigène Voir toutes AKAP10 Anticorps
- AKAP10 (A Kinase (PRKA) Anchor Protein 10 (AKAP10))
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Épitope
- N-Term
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Reactivité
- Humain, Rat, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp AKAP10 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Specificité
- AKAP10 Antibody detects endogenous levels of total AKAP10.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human AKAP10, corresponding to a region within N-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product AKAP10 Anticorps primaire
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- Indications d'application
- WB 1:500-1:1000, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- AKAP10 (A Kinase (PRKA) Anchor Protein 10 (AKAP10))
- Autre désignation
- AKAP10 (AKAP10 Produits)
- Synonymes
- anticorps MGC84612, anticorps AKAP10, anticorps fc10g11, anticorps wu:fc10g11, anticorps si:dkey-197m14.4, anticorps AKAP-10, anticorps D-AKAP-2, anticorps D-AKAP2, anticorps PRKA10, anticorps 1500031L16Rik, anticorps B130049N18Rik, anticorps D-akap2, anticorps Akap10, anticorps A-kinase anchoring protein 10, anticorps A-kinase anchoring protein 10 L homeolog, anticorps A kinase (PRKA) anchor protein 10, anticorps AKAP10, anticorps akap10.L, anticorps akap10, anticorps Akap10
- Sujet
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Description: Differentially targeted protein that binds to type I and II regulatory subunits of protein kinase A and anchors them to the mitochondria or the plasma membrane. Although the physiological relevance between PKA and AKAPS with mitochondria is not fully understood, one idea is that BAD, a proapoptotic member, is phosphorylated and inactivated by mitochondria-anchored PKA. It cannot be excluded too that it may facilitate PKA as well as G protein signal transduction, by acting as an adapter for assembling multiprotein complexes. With its RGS domain, it could lead to the interaction to G-alpha proteins, providing a link between the signaling machinery and the downstream kinase (By similarity).
Gene: AKAP10
- Poids moléculaire
- 73 kDa
- ID gène
- 11216
- UniProt
- O43572
- Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling
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