ING2 anticorps (C-Term)

N° du produit ABIN6257713

Détail du produit anti-ING2 anticorps

Antigène: ING2 (Inhibitor of Growth Family, Member 2 (ING2))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ING2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: ING2 Antibody detects endogenous levels of total ING2.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human ING2, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Date de péremption: 12 months

Détails sur ING2

Antigène: ING2 (Inhibitor of Growth Family, Member 2 (ING2))

Autre désignation: ING2 (ING2 Produits)

Synonymes: anticorps ING1L, anticorps p33ING2, anticorps 2810011M06Rik, anticorps Ing1l, anticorps Ing2b, anticorps P33ING2, anticorps ING2, anticorps INGX, anticorps wu:fe11c08, anticorps zgc:92346, anticorps ING1Lp, anticorps ing2, anticorps xing2, anticorps inhibitor of growth family member 2, anticorps inhibitor of growth family, member 2, anticorps inhibitor of growth family member 2 S homeolog, anticorps inhibitor of growth family member 2 L homeolog, anticorps ING2, anticorps Ing2, anticorps ing2.S, anticorps ing2, anticorps ing2.L

Sujet:

Description: Seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. Component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. ING2 activity seems to be modulated by binding to phosphoinositides (PtdInsPs).

Gene: ING2

Poids moléculaire: 33 kDa

ID gène: 3622

UniProt: Q9H160

Pathways: Chromatin Binding, Autophagy, Negative Regulation of intrinsic apoptotic Signaling