HOPX anticorps (C-Term)

N° du produit ABIN6257752

Détail du produit anti-HOPX anticorps

Antigène: HOPX (HOP Homeobox (HOPX))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HOPX est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: HOP Antibody detects endogenous levels of total HOP.

Homologie: Pig,Bovine,Horse,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human HOP, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Date de péremption: 12 months

Détails sur HOPX

Antigène: HOPX (HOP Homeobox (HOPX))

Autre désignation: HOPX (HOPX Produits)

Synonymes: anticorps CAMEO, anticorps HOD, anticorps HOP, anticorps LAGY, anticorps NECC1, anticorps OB1, anticorps SMAP31, anticorps TOTO, anticorps 1110018K11Rik, anticorps 1200015P04Rik, anticorps 2300002F06Rik, anticorps AI848177, anticorps AW490897, anticorps Cameo, anticorps Hdop, anticorps Hod, anticorps Hop, anticorps Ob1, anticorps Obl, anticorps Toto, anticorps GIIg15b, anticorps HOPX, anticorps hod, anticorps hop, anticorps ob1, anticorps lagy, anticorps toto, anticorps cameo, anticorps necc1, anticorps smap31, anticorps MGC147344, anticorps HOP homeobox, anticorps HOPX, anticorps Hopx, anticorps hopx

Sujet:

Description: Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy (By similarity). May act as a tumor suppressor. Acts as a co-chaperone for HSPA1A and HSPA1B chaperone proteins and assists in chaperone-mediated protein refolding (PubMed:27708256).

Gene: HOPX

Poids moléculaire: 8 kDa

ID gène: 84525

UniProt: Q9BPY8

Pathways: Regulation of Muscle Cell Differentiation