ESRP2 anticorps (N-Term)

N° du produit ABIN6257869

Détail du produit anti-ESRP2 anticorps

Antigène: ESRP2 (Epithelial Splicing Regulatory Protein 2 (ESRP2))

Épitope: N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ESRP2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: RBM35B Antibody detects endogenous levels of total RBM35B.

Homologie: Pig,Bovine,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human RBM35B, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Date de péremption: 12 months

Détails sur ESRP2

Antigène: ESRP2 (Epithelial Splicing Regulatory Protein 2 (ESRP2))

Autre désignation: ESRP2 (ESRP2 Produits)

Synonymes: anticorps RBM35B, anticorps 9530027K23Rik, anticorps Rbm35b, anticorps RGD1310855, anticorps cb404, anticorps fa07a06, anticorps rbm35b, anticorps sb:cb404, anticorps zgc:77254, anticorps epithelial splicing regulatory protein 2, anticorps microRNA 6773, anticorps ESRP2, anticorps Esrp2, anticorps MIR6773, anticorps esrp2

Sujet:

Description: mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.

Gene: ESRP2

Poids moléculaire: 78 kDa

ID gène: 80004

UniProt: Q9H6T0