TRIO anticorps (Internal Region)

N° du produit ABIN6257891

Détail du produit anti-TRIO anticorps

Antigène: TRIO (Triple Functional Domain Protein (TRIO))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIO est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC)

Specificité: TRIO Antibody detects endogenous levels of total TRIO.

Homologie: Pig,Zebrafish,Horse,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human TRIO, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Date de péremption: 12 months

Détails sur TRIO

Antigène: TRIO (Triple Functional Domain Protein (TRIO))

Autre désignation: TRIO (TRIO Produits)

Synonymes: anticorps ARHGEF23, anticorps tgat, anticorps 6720464I07Rik, anticorps AA408740, anticorps Solo, anticorps si:dz230d15.1, anticorps trio Rho guanine nucleotide exchange factor, anticorps triple functional domain (PTPRF interacting), anticorps trio Rho guanine nucleotide exchange factor b, anticorps TRIO, anticorps Trio, anticorps triob

Sujet:

Description: Guanine nucleotide exchange factor (GEF) for RHOA and RAC1 GTPases (PubMed:8643598, PubMed:27418539). Involved in coordinating actin remodeling, which is necessary for cell migration and growth (PubMed:10341202). In developing hippocampal neurons, limits dendrite formation, without affecting the establishment of axon polarity. Once dendrites are formed, involved in the control of synaptic function by regulating the endocytosis of AMPA-selective glutamate receptors (AMPARs) at CA1 excitatory synapses (By similarity). May act as a regulator of adipogenesis (By similarity).

Gene: TRIO

Poids moléculaire: 31 kDa

ID gène: 7204

UniProt: O75962