Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

CREB3L2 anticorps (Internal Region)

CREB3L2 Reactivité: Humain, Souris, Rat WB, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6257984
  • Antigène Voir toutes CREB3L2 Anticorps
    CREB3L2 (CAMP Responsive Element Binding Protein 3-Like 2 (CREB3L2))
    Épitope
    • 8
    • 7
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivité
    • 32
    • 8
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 29
    • 2
    • 2
    Lapin
    Clonalité
    • 31
    • 2
    Polyclonal
    Conjugué
    • 17
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CREB3L2 est non-conjugé
    Application
    • 26
    • 21
    • 5
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    CREB3L2 Antibody detects endogenous levels of total CREB3L2.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human CREB3L2, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product CREB3L2 Anticorps primaire
  • Indications d'application
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    CREB3L2 (CAMP Responsive Element Binding Protein 3-Like 2 (CREB3L2))
    Autre désignation
    CREB3L2 (CREB3L2 Produits)
    Synonymes
    anticorps CREB3L2, anticorps bbf2h7, anticorps BBF2H7, anticorps C530025K05Rik, anticorps Ra69, anticorps SCIRR69, anticorps zgc:158603, anticorps cAMP responsive element binding protein 3 like 2, anticorps cAMP responsive element binding protein 3-like 2, anticorps cAMP responsive element binding protein 3-like 2 L homeolog, anticorps CREB3L2, anticorps creb3l2, anticorps Creb3l2, anticorps creb3l2.L
    Sujet

    Description: Transcription factor involved in unfolded protein response (UPR). In the absence of endoplasmic reticulum (ER) stress, inserted into ER membranes, with N-terminal DNA-binding and transcription activation domains oriented toward the cytosolic face of the membrane. In response to ER stress, transported to the Golgi, where it is cleaved in a site-specific manner by resident proteases S1P/MBTPS1 and S2P/MBTPS2. The released N-terminal cytosolic domain is translocated to the nucleus to effect transcription of specific target genes. Plays a critical role in chondrogenesis by activating the transcription of SEC23A, which promotes the transport and secretion of cartilage matrix proteins, and possibly that of ER biogenesis-related genes (By similarity). In a neuroblastoma cell line, protects cells from ER stress-induced death (PubMed:17178827). In vitro activates transcription of target genes via direct binding to the CRE site (PubMed:17178827).

    Gene: CREB3L2

    Poids moléculaire
    58 kDa
    ID gène
    64764
    UniProt
    Q70SY1
    Pathways
    Thyroid Hormone Synthesis
Vous êtes ici:
Support technique