PRKG2 anticorps (N-Term)
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- Antigène Voir toutes PRKG2 Anticorps
- PRKG2 (Protein Kinase, CGMP-Dependent, Type II (PRKG2))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PRKG2 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificité
- CGK2 Antibody detects endogenous levels of total CGK2.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human CGK2, corresponding to a region within N-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product PRKG2 Anticorps primaire
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- Indications d'application
- WB 1:500-1:1000, ELISA(peptide) 1:20000-1:40000, IF/ICC 1:100-1:500
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- PRKG2 (Protein Kinase, CGMP-Dependent, Type II (PRKG2))
- Autre désignation
- PRKG2 (PRKG2 Produits)
- Synonymes
- anticorps MGC82580, anticorps PRKG2, anticorps si:dkey-18e17.2, anticorps PRKGR2, anticorps cGKII, anticorps GDPKII, anticorps AW212535, anticorps CGKII, anticorps Prkgr2, anticorps cGK-II, anticorps protein kinase, cGMP-dependent, type II, anticorps protein kinase, cGMP-dependent, type II L homeolog, anticorps cGMP-dependent protein kinase 2, anticorps PRKG2, anticorps prkg2.L, anticorps prkg2, anticorps LOC100541294, anticorps Prkg2
- Sujet
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Description: Crucial regulator of intestinal secretion and bone growth (By similarity). Phosphorylates and activates CFTR on the plasma membrane. Plays a key role in intestinal secretion by regulating cGMP-dependent translocation of CFTR in jejunum (By similarity). Acts downstream of NMDAR to activate the plasma membrane accumulation of GRIA1/GLUR1 in synapse and increase synaptic plasticity. Phosphorylates GRIA1/GLUR1 at Ser-863 (By similarity). Acts as regulator of gene expression and activator of the extracellular signal-regulated kinases MAPK3/ERK1 and MAPK1/ERK2 in mechanically stimulated osteoblasts. Under fluid shear stress, mediates ERK activation and subsequent induction of FOS, FOSL1/FRA1, FOSL2/FRA2 and FOSB that play a key role in the osteoblast anabolic response to mechanical stimulation (By similarity).
Gene: PRKG2
- Poids moléculaire
- 87 kDa
- ID gène
- 5593
- UniProt
- Q13237
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