DLX5 anticorps (Internal Region)

N° du produit ABIN6258115

Détail du produit anti-DLX5 anticorps

Antigène: DLX5 (Distal-Less Homeobox 5 (DLX5))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DLX5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: DLX5 Antibody detects endogenous levels of total DLX5.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human DLX5, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Références pour anticorps anti-DLX5 (ABIN6258115)

Miwa, Ito, Ohta: "Tsukushi is essential for the formation of the posterior semicircular canal that detects gait performance." dans: Journal of cell communication and signaling, (2021) (PubMed).

Détails sur DLX5

Antigène: DLX5 (Distal-Less Homeobox 5 (DLX5))

Autre désignation: DLX5 (DLX5 Produits)

Synonymes: anticorps SHFM1D, anticorps AI385752, anticorps RDLX, anticorps X-dll3, anticorps dll3, anticorps MGC69418, anticorps DLX5, anticorps dlx5, anticorps dlx4, anticorps zgc:101787, anticorps distal-less homeobox 5, anticorps distal-less homeobox 5 L homeolog, anticorps distal-less homeobox 2b, anticorps distal-less homeobox 5a, anticorps DLX5, anticorps Dlx5, anticorps dlx5.L, anticorps dlx5, anticorps dlx2b, anticorps dlx5a

Sujet:

Description: Transcriptional factor involved in bone development. Acts as an immediate early BMP-responsive transcriptional activator essential for osteoblast differentiation. Stimulates ALPL promoter activity in a RUNX2-independent manner during osteoblast differentiation. Stimulates SP7 promoter activity during osteoblast differentiation. Promotes cell proliferation by up-regulating MYC promoter activity. Involved as a positive regulator of both chondrogenesis and chondrocyte hypertrophy in the endochondral skeleton. Binds to the homeodomain-response element of the ALPL and SP7 promoter. Binds to the MYC promoter. Requires the 5'-TAATTA-3' consensus sequence for DNA-binding.

Gene: DLX5

Poids moléculaire: 32 kDa

ID gène: 1749

UniProt: P56178