GPR56 anticorps

N° du produit ABIN6258204

Détail du produit anti-GPR56 anticorps

Antigène: GPR56 (G Protein-Coupled Receptor 56 (GPR56))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GPR56 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: GPR56 antibody detects endogenous levels of total GPR56

Réactivité croisée: Humain

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Détails sur GPR56

Antigène: GPR56 (G Protein-Coupled Receptor 56 (GPR56))

Autre désignation: GPR56 (GPR56 Produits)

Synonymes: anticorps fc49b10, anticorps wu:fc49b10, anticorps BFPP, anticorps TM7LN4, anticorps TM7XN1, anticorps Cyt28, anticorps GPR56, anticorps adhesion G protein-coupled receptor G1, anticorps G protein-coupled receptor 56, anticorps ADGRG1, anticorps adgrg1, anticorps Adgrg1, anticorps GPR56

Sujet:

Description: Receptor involved in cell adhesion and probably in cell-cell interactions. Mediates cell matrix adhesion in developing neurons and hematopoietic stem cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basement membrane integrity and in cortical lamination (By similarity). Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12 (PubMed:22238662). Plays a role in the maintenance of hematopoietic stem cells and/or leukemia stem cells in bone marrow niche (By similarity). Plays a critical role in cancer progression by inhibiting VEGFA production threreby inhibiting angiogenesis through a signaling pathway mediated by PRKCA (PubMed:16757564, PubMed:21724588). Plays an essential role in testis development (By similarity).

Gene: ADGRG1

Poids moléculaire: 78 kDa

ID gène: 9289

UniProt: Q9Y653