PAEP anticorps

N° du produit ABIN6258298

Détail du produit anti-PAEP anticorps

Antigène: PAEP (Progestagen-Associated Endometrial Protein (PAEP))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAEP est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: PAEP antibody detects endogenous levels of total PAEP

Réactivité croisée: Humain, Rat (Rattus)

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Détails sur PAEP

Antigène: PAEP (Progestagen-Associated Endometrial Protein (PAEP))

Autre désignation: PAEP (PAEP Produits)

Synonymes: anticorps GD, anticorps GdA, anticorps GdF, anticorps GdS, anticorps PAEG, anticorps PEP, anticorps PP14, anticorps PAEP, anticorps Beta-LG, anticorps LGB, anticorps progestagen associated endometrial protein, anticorps progestagen-associated endometrial protein, anticorps PAEP, anticorps Paep

Sujet:

Description: Glycoprotein that regulates critical steps during fertilization and also has immunomonomodulatory effects. Four glycoforms, namely glycodelin-S, -A, -F and -C have been identified in reproductive tissues that differ in glycosylation and biological activity. Glycodelin-A has contraceptive and immunosuppressive activities (PubMed:9918684, PubMed:7531163). Glycodelin-C stimulates binding of spermatozoa to the zona pellucida (PubMed:17192260). Glycodelin-F inhibits spermatozoa-zona pellucida binding and significantly suppresses progesterone-induced acrosome reaction of spermatozoa (PubMed:12672671). Glycodelin-S in seminal plasma maintains the uncapacitated state of human spermatozoa (PubMed:15883155).

Gene: PAEP

Poids moléculaire: 21 kDa

ID gène: 5047

UniProt: P09466