UBE2D2 anticorps (C-Term)

N° du produit ABIN6258351

Détail du produit anti-UBE2D2 anticorps

Antigène: UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBE2D2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificité: UBE2D2 Antibody detects endogenous levels of total UBE2D2.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human UBE2D2, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur UBE2D2

Antigène: UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))

Autre désignation: UBE2D2 (UBE2D2 Produits)

Synonymes: anticorps E2(17)KB2, anticorps PUBC1, anticorps UBC4, anticorps UBC4/5, anticorps UBCH5B, anticorps 1500034D03Rik, anticorps Ubc2e, anticorps Ube2d2, anticorps ubc4, anticorps ube2d2, anticorps zgc:55886, anticorps E217kB, anticorps ubiquitin conjugating enzyme E2 D2, anticorps ubiquitin-conjugating enzyme E2D 2A, anticorps ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast), anticorps ubiquitin-conjugating enzyme E2D 2, anticorps ubiquitin conjugating enzyme E2 D3, anticorps UBE2D2, anticorps Ube2d2a, anticorps ube2d2, anticorps Ube2d2, anticorps UBE2D3

Sujet:

Description: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6. Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria by DDX58/RIG-I in response to viral infection. Essential for viral activation of IRF3.

Gene: UBE2D2

Poids moléculaire: 17 kDa

ID gène: 7322

UniProt: P62837

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades