UBR1 anticorps (Internal Region)

N° du produit ABIN6258376

Détail du produit anti-UBR1 anticorps

Antigène: UBR1 (Ubiquitin Protein Ligase E3 Component N-Recognin 1 (UBR1))

Épitope: Internal Region

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBR1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: UBR1 Antibody detects endogenous levels of total UBR1.

Homologie: Pig,Bovine,Horse,Sheep,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human UBR1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur UBR1

Antigène: UBR1 (Ubiquitin Protein Ligase E3 Component N-Recognin 1 (UBR1))

Autre désignation: UBR1 (UBR1 Produits)

Synonymes: anticorps Dmel\\CG9086, anticorps Ubr1, anticorps UBR1, anticorps JBS, anticorps AI504731, anticorps RGD1562326, anticorps Ubr1 ubiquitin ligase, anticorps ubiquitin protein ligase E3 component n-recognin 1, anticorps E3 ubiquitin-protein ligase ubr-1, anticorps Ubr1, anticorps ubr1, anticorps UBR1, anticorps ubr-1

Sujet:

Description: E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. May be involved in pancreatic homeostasis. Binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth.

Gene: UBR1

Poids moléculaire: 36 kDa

ID gène: 197131

UniProt: Q8IWV7