ABHD2 anticorps (Internal Region)

N° du produit ABIN6258379

Détail du produit anti-ABHD2 anticorps

Antigène: ABHD2 (Abhydrolase Domain Containing 2 (ABHD2))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ABHD2 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: ABHD2 Antibody detects endogenous levels of total ABHD2.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human ABHD2, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur ABHD2

Antigène: ABHD2 (Abhydrolase Domain Containing 2 (ABHD2))

Autre désignation: ABHD2 (ABHD2 Produits)

Synonymes: anticorps HS1-2, anticorps LABH2, anticorps PHPS1-2, anticorps abhd2, anticorps zgc:55722, anticorps 2210009N18Rik, anticorps Labh-2, anticorps zgc:153750, anticorps abhydrolase domain containing 2, anticorps abhydrolase domain containing 2a, anticorps abhydrolase domain containing 2b, anticorps ABHD2, anticorps Abhd2, anticorps abhd2a, anticorps abhd2, anticorps abhd2b

Sujet:

Description: Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane (PubMed:26989199). Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1-arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA) (PubMed:26989199). Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2AG, an inhibitor of the sperm calcium channel CatSper, leading to calcium influx via CatSper and sperm activation (PubMed:26989199). May also play a role in smooth muscle cells migration (By similarity).

Gene: ABHD2

Poids moléculaire: 48 kDa

ID gène: 11057

UniProt: P08910