Chp2 anticorps (Internal Region)
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- Antigène Tous les produits Chp2
- Chp2
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Épitope
- Internal Region
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Chp2 est non-conjugé
- Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
- Specificité
- CHP2 Antibody detects endogenous levels of total CHP2.
- Homologie
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human CHP2, corresponding to a region within the internal amino acids.
- Isotype
- IgG
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- Indications d'application
- WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- Chp2
- Abstract
- Chp2 Produits
- Synonymes
- anticorps 2010110P09Rik, anticorps Cbhp2, anticorps chp-2, anticorps calcineurin-like EF hand protein 2, anticorps calcineurin like EF-hand protein 2, anticorps Chp2, anticorps CHP2
- Sujet
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Description: Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na+/H+ exchange activity. Binds to and activates SLC9A1/NHE1 in a serum-independent manner, thus increasing pH and protecting cells from serum deprivation-induced death. Also plays a role in the regulation of cell proliferation and tumor growth by increasing the phosphatase activity of PPP3CA in a calcium-dependent manner. Activator of the calcineurin/NFAT signaling pathway. Involved in the cytoplasmic translocation of the transcription factor NFATC3 to the nucleus.
Gene: CHP2
- Poids moléculaire
- 22 kDa
- ID gène
- 63928
- UniProt
- O43745
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