RNF144B anticorps (Internal Region)

N° du produit ABIN6258475

Détail du produit anti-RNF144B anticorps

Antigène: RNF144B (Ring Finger Protein 144B (RNF144B))

Épitope: Internal Region

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF144B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: RNF144B Antibody detects endogenous levels of total RNF144B.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human RNF144B, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur RNF144B

Antigène: RNF144B (Ring Finger Protein 144B (RNF144B))

Autre désignation: RNF144B (RNF144B Produits)

Synonymes: anticorps IBRDC2, anticorps PIR2, anticorps bA528A10.3, anticorps p53RFP, anticorps BC025007, anticorps E130105P19Rik, anticorps Ibrdc2, anticorps Pir2, anticorps ring finger protein 144B, anticorps RNF144B, anticorps Rnf144b

Sujet:

Description: E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a p53/TP53-dependent but caspase-independent mechanism. However, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, a pro-apoptotic protein, ultimately leading to protection of cell death, But, it is not an anti-apoptotic protein per se.

Gene: RNF144B

Poids moléculaire: 33 kDa

ID gène: 255488

UniProt: Q7Z419