TSEN54 anticorps (Internal Region)

N° du produit ABIN6258653

Détail du produit anti-TSEN54 anticorps

Antigène: TSEN54 (tRNA Splicing Endonuclease 54 (TSEN54))

Épitope: Internal Region

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TSEN54 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: TSEN54 Antibody detects endogenous levels of total TSEN54.

Homologie: Bovine

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human TSEN54, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur TSEN54

Antigène: TSEN54 (tRNA Splicing Endonuclease 54 (TSEN54))

Autre désignation: TSEN54 (TSEN54 Produits)

Synonymes: anticorps zgc:109927, anticorps 0610034P02Rik, anticorps PCH2A, anticorps PCH4, anticorps SEN54L, anticorps sen54, anticorps tRNA splicing endonuclease subunit 54, anticorps TSEN54 tRNA splicing endonuclease subunit, anticorps tRNA splicing endonuclease 54 homolog (S. cerevisiae), anticorps TSEN54, anticorps tsen54, anticorps Tsen54

Sujet:

Description: Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3'-end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3'-end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events.

Gene: TSEN54

Poids moléculaire: 59 kDa

ID gène: 283989

UniProt: Q7Z6J9

Pathways: Synaptic Membrane