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CDK5R1 anticorps (N-Term)

CDK5R1 Reactivité: Humain, Souris, Rat WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6258750
  • Antigène Voir toutes CDK5R1 Anticorps
    CDK5R1 (Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1))
    Épitope
    • 16
    • 10
    • 9
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 54
    • 47
    • 20
    • 12
    • 11
    • 10
    • 10
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 51
    • 17
    • 1
    Lapin
    Clonalité
    • 45
    • 24
    Polyclonal
    Conjugué
    • 24
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CDK5R1 est non-conjugé
    Application
    • 54
    • 37
    • 33
    • 16
    • 14
    • 13
    • 13
    • 10
    • 6
    • 5
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    CDK5R1/P35 Antibody detects endogenous levels of total CDK5R1/P35.
    Homologie
    Pig,Bovine,Horse,Sheep,Dog,Chicken,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human CDK5R1/P35, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product CDK5R1 Anticorps primaire
  • Indications d'application
    WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    CDK5R1 (Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1))
    Autre désignation
    CDK5R1 (CDK5R1 Produits)
    Synonymes
    anticorps CDK5P35, anticorps CDK5R, anticorps NCK5A, anticorps p23, anticorps p25, anticorps p35, anticorps p35nck5a, anticorps cdk5r1, anticorps zgc:92814, anticorps CDK5R1, anticorps Cdk5r, anticorps P25/P35, anticorps D11Bwg0379e, anticorps Xp35.1, anticorps cyclin dependent kinase 5 regulatory subunit 1, anticorps cyclin-dependent kinase 5, regulatory subunit 1b (p35), anticorps cyclin-dependent kinase 5 regulatory subunit 1, anticorps S100 calcium binding protein A9, anticorps cyclin-dependent kinase 5, regulatory subunit 1 (p35), anticorps cyclin-dependent kinase 5, regulatory subunit 1 (p35) L homeolog, anticorps CDK5R1, anticorps cdk5r1b, anticorps Cdk5r1, anticorps S100A9, anticorps cdk5r1.L
    Classe de substances
    Viral Protein
    Sujet

    Description: p35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required for neurite outgrowth and cortical lamination. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. Activator of TPKII. The complex p35/CDK5 participates in the regulation of the circadian clock by modulating the function of CLOCK protein: phosphorylates CLOCK at 'Thr-451' and 'Thr-461' and regulates the transcriptional activity of the CLOCK-ARNTL/BMAL1 heterodimer in association with altered stability and subcellular distribution.

    Gene: CDK5R1

    Poids moléculaire
    38 kDa
    ID gène
    8851
    UniProt
    Q15078
    Pathways
    Stem Cell Maintenance, Regulation of Cell Size, Positive Regulation of Endopeptidase Activity
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