SETDB2 anticorps (N-Term)

N° du produit ABIN6258755

Détail du produit anti-SETDB2 anticorps

Antigène: SETDB2 (SET Domain, Bifurcated 2 (SETDB2))

Épitope: N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SETDB2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: SETDB2 Antibody detects endogenous levels of total SETDB2.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human SETDB2, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Date de péremption: 12 months

Détails sur SETDB2

Antigène: SETDB2 (SET Domain, Bifurcated 2 (SETDB2))

Autre désignation: SETDB2 (SETDB2 Produits)

Synonymes: anticorps C13orf4, anticorps CLLD8, anticorps CLLL8, anticorps KMT1F, anticorps Clld8, anticorps Gm293, anticorps SET domain bifurcated 2, anticorps SET domain, bifurcated 2, anticorps SETDB2, anticorps Setdb2

Sujet:

Description: Histone methyltransferase involved in left-right axis specification in early development and mitosis. Specifically trimethylates 'Lys-9' of histone H3 (H3K9me3). H3K9me3 is a specific tag for epigenetic transcriptional repression that recruits HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Contributes to H3K9me3 in both the interspersed repetitive elements and centromere-associated repeats. Plays a role in chromosome condensation and segregation during mitosis.

Gene: SETDB2

Poids moléculaire: 120 kDa

ID gène: 83852

UniProt: Q96T68