FOLR1 anticorps (Internal Region)

N° du produit ABIN6258796

Détail du produit anti-FOLR1 anticorps

Antigène: FOLR1 (Folate Receptor 1 (Adult) (FOLR1))

Épitope: Internal Region

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOLR1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificité: FOLR1 Antibody detects endogenous levels of total FOLR1.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human FOLR1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur FOLR1

Antigène: FOLR1 (Folate Receptor 1 (Adult) (FOLR1))

Autre désignation: FOLR1 (FOLR1 Produits)

Synonymes: anticorps FBP, anticorps FOLR, anticorps fbp, anticorps folr, anticorps folr1, anticorps FBP1, anticorps Folbp-1, anticorps Folbp1, anticorps Fbp1, anticorps FOLR1, anticorps Folr1, anticorps folate receptor 1, anticorps folate receptor 1 (adult), anticorps folate receptor 1 (adult) L homeolog, anticorps zgc:165502, anticorps Folate receptor alpha, anticorps folate receptor alpha, anticorps FOLR1, anticorps folr1, anticorps folr1.L, anticorps zgc:165502, anticorps Folr1, anticorps LOC100066084, anticorps LOC100725439

Sujet:

Description: Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral  pH . Exposure to slightly acidic  pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation.

Gene: FOLR1

Poids moléculaire: 34 kDa

ID gène: 2348

UniProt: P15328

Pathways: Dicarboxylic Acid Transport