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Manic Fringe anticorps (Internal Region)

MFNG Reactivité: Humain, Souris, Rat WB, ELISA, ICC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6258883
  • Antigène Voir toutes Manic Fringe (MFNG) Anticorps
    Manic Fringe (MFNG) (MFNG)
    Épitope
    • 16
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivité
    • 27
    • 25
    • 9
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 40
    • 4
    • 1
    Lapin
    Clonalité
    • 44
    • 1
    Polyclonal
    Conjugué
    • 21
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Manic Fringe est non-conjugé
    Application
    • 19
    • 14
    • 13
    • 13
    • 13
    • 6
    • 5
    • 4
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificité
    MFNG Antibody detects endogenous levels of total MFNG.
    Homologie
    Pig,Bovine,Horse,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human MFNG, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product MFNG Anticorps primaire
  • Indications d'application
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    Manic Fringe (MFNG) (MFNG)
    Autre désignation
    MFNG (MFNG Produits)
    Synonymes
    anticorps AW546563, anticorps MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase, anticorps MFNG, anticorps Mfng
    Sujet

    Description: Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules (PubMed:10935626). Modulates NOTCH1 activity by modifying O-fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1 (By similarity).

    Gene: MFNG

    Poids moléculaire
    38 kDa
    ID gène
    4242
    UniProt
    O00587
    Pathways
    Signalisation Notch
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