GLRB anticorps (Internal Region)
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- Antigène Voir toutes GLRB Anticorps
- GLRB (Glycine Receptor, beta (GLRB))
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Épitope
- Internal Region
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GLRB est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
- Specificité
- GLRB Antibody detects endogenous levels of total GLRB.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human GLRB, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product GLRB Anticorps primaire
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- Indications d'application
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- GLRB (Glycine Receptor, beta (GLRB))
- Autre désignation
- GLRB (GLRB Produits)
- Synonymes
- anticorps HKPX2, anticorps glrb, anticorps MGC145156, anticorps AI853901, anticorps Glyrb, anticorps spa, anticorps spastic, anticorps glrb2, anticorps zgc:101041, anticorps glycine receptor beta, anticorps glycine receptor, beta, anticorps glycine receptor, beta subunit, anticorps glycine receptor, beta b, anticorps GLRB, anticorps Glrb, anticorps glrb, anticorps glrbb
- Sujet
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Description: Glycine receptors are ligand-gated chloride channels. GLRB does not form ligand-gated ion channels by itself, but is part of heteromeric ligand-gated chloride channels. Channel opening is triggered by extracellular glycine (PubMed:8717357, PubMed:15302677, PubMed:16144831, PubMed:22715885, PubMed:25445488, PubMed:11929858, PubMed:23238346). Heteropentameric channels composed of GLRB and GLRA1 are activated by lower glycine levels than homopentameric GLRA1 (PubMed:8717357). Plays an important role in the down-regulation of neuronal excitability (PubMed:11929858, PubMed:23238346). Contributes to the generation of inhibitory postsynaptic currents (PubMed:25445488).
Gene: GLRB
- Poids moléculaire
- 56 kDa
- ID gène
- 2743
- UniProt
- P48167
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