PARP2 anticorps (Internal Region)

N° du produit ABIN6259061

Détail du produit anti-PARP2 anticorps

Antigène: PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))

Épitope: Internal Region

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PARP2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: PARP2 Antibody detects endogenous levels of total PARP2.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human PARP2, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur PARP2

Antigène: PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))

Autre désignation: PARP2 (PARP2 Produits)

Synonymes: anticorps ADPRT2, anticorps ADPRTL2, anticorps ADPRTL3, anticorps ARTD2, anticorps PARP-2, anticorps pADPRT-2, anticorps Adprt2, anticorps Adprtl2, anticorps Aspartl2, anticorps C78626, anticorps cb996, anticorps adprtl2, anticorps ADPRT-2, anticorps APP, anticorps ATPARP1, anticorps PARP1, anticorps POLY(ADP-RIBOSE) POLYMERASE, anticorps POLY(ADP-RIBOSE) POLYMERASE 1, anticorps PP, anticorps T14P8.19, anticorps T14P8_19, anticorps poly(ADP-ribose) polymerase, anticorps poly(ADP-ribose) polymerase 2, anticorps poly(ADP-ribose) polymerase 2, anticorps poly (ADP-ribose) polymerase family, member 2, anticorps poly (ADP-ribose) polymerase 2, anticorps poly(ADP-ribose) polymerase 2 S homeolog, anticorps poly(ADP-ribose) polymerase, anticorps PARP2, anticorps Parp2, anticorps parp2, anticorps parp2.S

Sujet:

Description: Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism (PubMed:10364231, PubMed:28190768). This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks (PubMed:10364231). Mediates serine ADP-ribosylation of target proteins following interaction with HPF1, HPF1 conferring serine specificity (PubMed:28190768).

Gene: PARP2

Poids moléculaire: 75 kDa

ID gène: 10038

UniProt: Q9UGN5

Pathways: Réparation de l'ADN