MRGPRX1 anticorps (C-Term)

N° du produit ABIN6259084

Détail du produit anti-MRGPRX1 anticorps

Antigène: MRGPRX1 (MAS-Related GPR, Member X1 (MRGPRX1))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MRGPRX1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: MRGX1 Antibody detects endogenous levels of total MRGX1.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human MRGX1, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur MRGPRX1

Antigène: MRGPRX1 (MAS-Related GPR, Member X1 (MRGPRX1))

Autre désignation: MRGPRX1 (MRGPRX1 Produits)

Synonymes: anticorps GPCR, anticorps MRGX1, anticorps SNSR4, anticorps MrgC11, anticorps Mrgprc11, anticorps Snsr1, anticorps MAS related GPR family member X1, anticorps MAS-related GPR, member X1, anticorps MRGPRX1, anticorps Mrgprx1

Sujet:

Description: Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22)(PubMed:26582731). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway. Activated by the antimalarial drug, chloroquine. May mediate chloroquine-induced itch, in a histamine-independent manner.

Gene: MRGPRX1

Poids moléculaire: 36 kDa

ID gène: 259249

UniProt: Q96LB2