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MRGPRX1 anticorps (C-Term)

MRGPRX1 Reactivité: Humain WB, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6259084
  • Antigène Voir toutes MRGPRX1 Anticorps
    MRGPRX1 (MAS-Related GPR, Member X1 (MRGPRX1))
    Épitope
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 15
    • 8
    • 4
    • 1
    Humain
    Hôte
    • 23
    Lapin
    Clonalité
    • 23
    Polyclonal
    Conjugué
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MRGPRX1 est non-conjugé
    Application
    • 12
    • 6
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    MRGX1 Antibody detects endogenous levels of total MRGX1.
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human MRGX1, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product MRGPRX1 Anticorps primaire
  • Indications d'application
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    MRGPRX1 (MAS-Related GPR, Member X1 (MRGPRX1))
    Autre désignation
    MRGPRX1 (MRGPRX1 Produits)
    Synonymes
    anticorps GPCR, anticorps MRGX1, anticorps SNSR4, anticorps MrgC11, anticorps Mrgprc11, anticorps Snsr1, anticorps MAS related GPR family member X1, anticorps MAS-related GPR, member X1, anticorps MRGPRX1, anticorps Mrgprx1
    Sujet

    Description: Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22)(PubMed:26582731). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway. Activated by the antimalarial drug, chloroquine. May mediate chloroquine-induced itch, in a histamine-independent manner.

    Gene: MRGPRX1

    Poids moléculaire
    36 kDa
    ID gène
    259249
    UniProt
    Q96LB2
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