STK24 anticorps (N-Term)

N° du produit ABIN6259111

Détail du produit anti-STK24 anticorps

Antigène: STK24 (serine/threonine Kinase 24 (STK24))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STK24 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: MST3 Antibody detects endogenous levels of total MST3.

Homologie: Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human MST3, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IHC: 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur STK24

Antigène: STK24 (serine/threonine Kinase 24 (STK24))

Autre désignation: STK24 (STK24 Produits)

Synonymes: anticorps MST3, anticorps MST3B, anticorps STE20, anticorps STK3, anticorps 1810013H02Rik, anticorps C76483, anticorps MST-3, anticorps Mst3, anticorps Mst3b, anticorps RGD1561742, anticorps stk24, anticorps wu:fi29b08, anticorps zgc:66137, anticorps 0610042I06Rik, anticorps MST, anticorps Mst2, anticorps Ste20, anticorps mess1, anticorps zgc:163071, anticorps mst3, anticorps mst3b, anticorps ste20, anticorps stk3, anticorps serine/threonine kinase 24, anticorps serine/threonine kinase 24b (STE20 homolog, yeast), anticorps serine/threonine-protein kinase 24, anticorps serine/threonine kinase 3, anticorps serine/threonine kinase 24a (STE20 homolog, yeast), anticorps serine/threonine kinase 24 L homeolog, anticorps STK24, anticorps Stk24, anticorps stk24b, anticorps ATEG_04314, anticorps ATEG_09179, anticorps UREG_03984, anticorps BDBG_07988, anticorps MCYG_07323, anticorps Stk3, anticorps stk24a, anticorps stk24.L

Sujet:

Description: Serine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation. Mediates oxidative-stress-induced cell death by modulating phosphorylation of JNK1-JNK2 (MAPK8 and MAPK9), p38 (MAPK11, MAPK12, MAPK13 and MAPK14) during oxidative stress. Plays a role in a staurosporine-induced caspase-independent apoptotic pathway by regulating the nuclear translocation of AIFM1 and ENDOG and the DNase activity associated with ENDOG. Phosphorylates STK38L on 'Thr-442' and stimulates its kinase activity. In association with STK26 negatively regulates Golgi reorientation in polarized cell migration upon RHO activation (PubMed:27807006). Regulates also cellular migration with alteration of PTPN12 activity and PXN phosphorylation: phosphorylates PTPN12 and inhibits its activity and may regulate PXN phosphorylation through PTPN12. May act as a key regulator of axon regeneration in the optic nerve and radial nerve.

Gene: STK24

Poids moléculaire: 50 kDa

ID gène: 8428

UniProt: Q9Y6E0