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MORG1 anticorps (Internal Region)

wdr83 Reactivité: Humain, Rat, Souris WB, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6259117
  • Antigène Voir toutes MORG1 (wdr83) Anticorps
    MORG1 (wdr83) (WD Repeat Domain 83 (wdr83))
    Épitope
    • 15
    • 8
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Internal Region
    Reactivité
    • 39
    • 33
    • 32
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Rat, Souris
    Hôte
    • 49
    • 5
    Lapin
    Clonalité
    • 52
    • 2
    Polyclonal
    Conjugué
    • 22
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MORG1 est non-conjugé
    Application
    • 39
    • 19
    • 13
    • 13
    • 9
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    MORG1 Antibody detects endogenous levels of total MORG1.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human MORG1, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product wdr83 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Date de péremption
    12 months
  • Antigène
    MORG1 (wdr83) (WD Repeat Domain 83 (wdr83))
    Autre désignation
    WDR83 (wdr83 Produits)
    Synonymes
    anticorps MORG1, anticorps 1500041N16Rik, anticorps Morg1, anticorps RGD1306947, anticorps morg1, anticorps MAPK organizer 1, anticorps wu:fj29g04, anticorps zgc:92654, anticorps WD repeat domain 83, anticorps WD repeat domain containing 83, anticorps WD repeat domain 83 L homeolog, anticorps WDR83, anticorps Wdr83, anticorps wdr83.L, anticorps wdr83
    Sujet

    Description: Molecular scaffold protein for various multimeric protein complexes. Acts as a module in the assembly of a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists. At low concentrations it enhances ERK activation, whereas high concentrations lead to the inhibition of ERK activation. Also involved in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha via its interaction with EGLN3/PHD3. May promote degradation of HIF1A. May act by recruiting signaling complexes to a specific upstream activator (By similarity). May also be involved in pre-mRNA splicing.

    Gene: WDR83

    Poids moléculaire
    34 kDa
    ID gène
    84292
    UniProt
    Q9BRX9
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