TUSC3 anticorps (Internal Region)

N° du produit ABIN6259118

Détail du produit anti-TUSC3 anticorps

Antigène: TUSC3 (Tumor Suppressor Candidate 3 (TUSC3))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TUSC3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: TUSC3 Antibody detects endogenous levels of total TUSC3.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human TUSC3, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur TUSC3

Antigène: TUSC3 (Tumor Suppressor Candidate 3 (TUSC3))

Autre désignation: TUSC3 (TUSC3 Produits)

Synonymes: anticorps zgc:110044, anticorps D8S1992, anticorps M33, anticorps MRT22, anticorps MRT7, anticorps N33, anticorps OST3A, anticorps AU022242, anticorps BC003311, anticorps tumor suppressor candidate 3, anticorps tumor suppressor candidate 3 L homeolog, anticorps TUSC3, anticorps tusc3, anticorps tusc3.L, anticorps CpipJ_CPIJ005611, anticorps Tusc3

Sujet:

Description: Acts as accessory component of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. Involved in N-glycosylation of STT3B-dependent substrates. Specifically required for the glycosylation of a subset of acceptor sites that are near cysteine residues, in this function seems to act redundantly with MAGT1. In its oxidized form proposed to form transient mixed disulfides with a glycoprotein substrate to facilitate access of STT3B to the unmodified acceptor site. Has also oxidoreductase-independent functions in the STT3B-containing OST complex possibly involving substrate recognition.

Gene: TUSC3

Poids moléculaire: 39 kDa

ID gène: 7991

UniProt: Q13454

Pathways: Cell RedoxHomeostasis