PAX4 anticorps (Internal Region)
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- Antigène Voir toutes PAX4 Anticorps
- PAX4 (Paired Box 4 (PAX4))
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Épitope
- Internal Region
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PAX4 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificité
- PAX4 Antibody detects endogenous levels of total PAX4.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human PAX4, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product PAX4 Anticorps primaire
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- Indications d'application
- WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Date de péremption
- 12 months
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- Antigène
- PAX4 (Paired Box 4 (PAX4))
- Autre désignation
- PAX4 (PAX4 Produits)
- Synonymes
- anticorps KPD, anticorps MODY9, anticorps Pax-4, anticorps PAX4, anticorps paired box 4, anticorps PAX4, anticorps Pax4
- Sujet
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Description: Plays an important role in the differentiation and development of pancreatic islet beta cells. Transcriptional repressor that binds to a common element in the glucagon, insulin and somatostatin promoters. Competes with PAX6 for this same promoter binding site. Isoform 2 appears to be a dominant negative form antagonizing PAX4 transcriptional activity.
Gene: PAX4
- Poids moléculaire
- 42 kDa
- ID gène
- 5078
- UniProt
- O43316
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