PPHLN1 anticorps (N-Term)

N° du produit ABIN6259270

Détail du produit anti-PPHLN1 anticorps

Antigène: PPHLN1 (Periphilin 1 (PPHLN1))

Épitope: N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPHLN1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: PPHLN Antibody detects endogenous levels of total PPHLN.

Homologie: Pig,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human PPHLN, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur PPHLN1

Antigène: PPHLN1 (Periphilin 1 (PPHLN1))

Autre désignation: PPHLN1 (PPHLN1 Produits)

Synonymes: anticorps MGC75908, anticorps MGC81987, anticorps wu:fb83c09, anticorps zgc:158246, anticorps si:ch211-155a11.2, anticorps HSPC232, anticorps 1110063K05Rik, anticorps 1600022A19Rik, anticorps CR, anticorps HSPC206, anticorps periphilin 1, anticorps periphilin 1 S homeolog, anticorps PPHLN1, anticorps pphln1, anticorps pphln1.S, anticorps Pphln1

Sujet:

Description: Component of the HUSH complex, a multiprotein complex that mediates epigenetic repression. The HUSH complex is recruited to genomic loci rich in H3K9me3 and is probably required to maintain transcriptional silencing by promoting recruitment of SETDB1, a histone methyltransferase that mediates further deposition of H3K9me3. In the HUSH complex, contributes to the maintenance of the complex at chromatin (PubMed:26022416). Acts as a transcriptional corepressor and regulates the cell cycle, probably via the HUSH complex (PubMed:15474462, PubMed:17963697). May be involved in epithelial differentiation by contributing to epidermal integrity and barrier formation (Probable).

Gene: PPHLN1

Poids moléculaire: 53 kDa

ID gène: 51535

UniProt: Q8NEY8