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ALKBH5 anticorps (Internal Region)

ALKBH5 Reactivité: Humain, Souris, Rat WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6259460
  • Antigène Voir toutes ALKBH5 Anticorps
    ALKBH5 (AlkB, Alkylation Repair Homolog 5 (ALKBH5))
    Épitope
    • 15
    • 7
    • 6
    • 6
    • 6
    • 2
    • 1
    Internal Region
    Reactivité
    Humain, Souris, Rat
    Hôte
    • 38
    • 2
    Lapin
    Clonalité
    • 40
    Polyclonal
    Conjugué
    • 9
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ALKBH5 est non-conjugé
    Application
    • 18
    • 17
    • 13
    • 13
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Specificité
    ALKBH5 Antibody detects endogenous levels of total ALKBH5.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human ALKBH5, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product ALKBH5 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Date de péremption
    12 months
  • Antigène
    ALKBH5 (AlkB, Alkylation Repair Homolog 5 (ALKBH5))
    Autre désignation
    ALKBH5 (ALKBH5 Produits)
    Synonymes
    anticorps RGD1309496, anticorps ABH5, anticorps OFOXD, anticorps OFOXD1, anticorps AW050020, anticorps AW215868, anticorps Abh5, anticorps E130207K11, anticorps Ofoxd, anticorps alkB homolog 5, RNA demethylase, anticorps alkB homolog 5, RNA demethylase L homeolog, anticorps Alkbh5, anticorps alkbh5.L, anticorps ALKBH5
    Sujet

    Description: Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N6-methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes (PubMed:23177736, PubMed:24778178, PubMed:24616105, PubMed:24489119). Can also demethylate N6-methyladenosine in single-stranded DNA (in vitro) (PubMed:24616105). Requires molecular oxygen, alpha-ketoglutarate and iron (PubMed:21264265, PubMed:23177736, PubMed:24778178, PubMed:24616105, PubMed:24489119). Demethylation of m6A mRNA affects mRNA processing and export (PubMed:23177736). Required for spermatogenesis (By similarity).

    Gene: ALKBH5

    Poids moléculaire
    ?44 kDa
    ID gène
    54890
    UniProt
    Q6P6C2
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