ATG4D anticorps (C-Term)

N° du produit ABIN6259487

Détail du produit anti-ATG4D anticorps

Antigène: ATG4D (Autophagy related 4D Cysteine Peptidase (ATG4D))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATG4D est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: ATG4D Antibody detects endogenous levels of total ATG4D.

Homologie: Pig,Horse,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human ATG4D, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur ATG4D

Antigène: ATG4D (Autophagy related 4D Cysteine Peptidase (ATG4D))

Autre désignation: ATG4D (ATG4D Produits)

Synonymes: anticorps APG4-D, anticorps APG4D, anticorps AUTL4, anticorps 9830134P12Rik, anticorps Apg4d, anticorps Atg4dl, anticorps Autl4, anticorps apg4d, anticorps autophagy related 4D cysteine peptidase, anticorps autophagy related 4D, cysteine peptidase, anticorps autophagy related 4D, cysteine peptidase L homeolog, anticorps ATG4D, anticorps Atg4d, anticorps atg4d.L

Sujet:

Description: Cysteine protease ATG4D: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.

Gene: ATG4D

Poids moléculaire: 53 kDa

ID gène: 84971

UniProt: Q86TL0

Pathways: Autophagy