WEE2 anticorps
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- Antigène Voir toutes WEE2 Anticorps
- WEE2 (WEE1 Homolog 2 (S. Pombe) (WEE2))
- Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp WEE2 est non-conjugé
- Application
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
- Specificité
- WEE2 Antibody detects endogenous levels of total WEE2
- Réactivité croisée
- Humain, Souris
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide
- Isotype
- IgG
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- Indications d'application
- WB 1:500~1:1000, IF/ICC 1:100-1:500
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C.Stable for 12 months from date of receipt
- Date de péremption
- 12 months
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- Antigène
- WEE2 (WEE1 Homolog 2 (S. Pombe) (WEE2))
- Autre désignation
- WEE2 (WEE2 Produits)
- Synonymes
- anticorps Xe-wee1, anticorps wee1, anticorps wee1-b, anticorps wee1a, anticorps wee1b, anticorps wee2-b, anticorps xwee1, anticorps xwee2, anticorps WEE1B, anticorps Gm1065, anticorps Wee1B, anticorps WEE2, anticorps im:5913035, anticorps si:ch211-238n5.5, anticorps wu:fi13b10, anticorps zgc:123074, anticorps WEE1 homolog 2, anticorps WEE1 homolog 2 (S. pombe), anticorps wee2, anticorps WEE2, anticorps Wee2
- Sujet
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Description: Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key regulator of meiosis during both prophase I and metaphase II. Required to maintain meiotic arrest in oocytes during the germinal vesicle (GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and promote pronuclear formation (By similarity).
Gene: WEE2
- Poids moléculaire
- 60 kDa
- ID gène
- 494551
- UniProt
- P0C1S8
- Pathways
- M Phase
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