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WEE2 anticorps

WEE2 Reactivité: Humain, Souris WB, ELISA, ICC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6259536
  • Antigène Voir toutes WEE2 Anticorps
    WEE2 (WEE1 Homolog 2 (S. Pombe) (WEE2))
    Reactivité
    Humain, Souris
    Hôte
    • 25
    Lapin
    Clonalité
    • 25
    Polyclonal
    Conjugué
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp WEE2 est non-conjugé
    Application
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificité
    WEE2 Antibody detects endogenous levels of total WEE2
     Réactivité croisée
    Humain, Souris
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide
    Isotype
    IgG
  • Indications d'application
    WB 1:500~1:1000, IF/ICC 1:100-1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C.Stable for 12 months from date of receipt
    Date de péremption
    12 months
  • Antigène
    WEE2 (WEE1 Homolog 2 (S. Pombe) (WEE2))
    Autre désignation
    WEE2 (WEE2 Produits)
    Synonymes
    anticorps Xe-wee1, anticorps wee1, anticorps wee1-b, anticorps wee1a, anticorps wee1b, anticorps wee2-b, anticorps xwee1, anticorps xwee2, anticorps WEE1B, anticorps Gm1065, anticorps Wee1B, anticorps WEE2, anticorps im:5913035, anticorps si:ch211-238n5.5, anticorps wu:fi13b10, anticorps zgc:123074, anticorps WEE1 homolog 2, anticorps WEE1 homolog 2 (S. pombe), anticorps wee2, anticorps WEE2, anticorps Wee2
    Sujet

    Description: Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key regulator of meiosis during both prophase I and metaphase II. Required to maintain meiotic arrest in oocytes during the germinal vesicle (GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and promote pronuclear formation (By similarity).

    Gene: WEE2

    Poids moléculaire
    60 kDa
    ID gène
    494551
    UniProt
    P0C1S8
    Pathways
    M Phase
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